What causes papular pruritic eruption?

Etiology. The pathophysiology of papular pruritic eruption is not completely understood. Hypersensitivity to arthropod bites and a form of chronic recall reaction to arthropod antigens in the setting of HIV-associated immune dysregulation has been suggested (Penneys et al., 1989).

What is pruritic papule?

Pruritic papular eruption (PPE) is a skin disease characterized by the eruption of itching papules on the extremities, face, and trunk; it is quite frequent in HIV-positive patients especially during the advanced immunosuppressive stage.

What blood causes itching?

Itch is common in people who have a disease that affects their blood, such as Hodgkin’s lymphoma or cutaneous T-cell lymphoma. It can also be a sign of advanced kidney disease and often develops in people who are close to needing dialysis or currently receiving dialysis.

What is papular lesion?

A papular lesion is a solid, raised area, usually less than 1 cm in diameter, with distinct borders. The papule may be pink, red, violaceous, flesh colored, and hyperpigmented or hypopigmented. Papulosquamous disorders describe skin lesions with papules that have an accompanying scale.

What is an example of a papule?

Papules are elevated lesions usually < 10 mm in diameter that can be felt or palpated. Examples include nevi, warts, lichen planus. read more , insect bites, seborrheic keratoses.

Are papules painful?

Papules are an inflammatory form of acne. They don’t have a pus-filled tip, but they’re still noticeable. They may be red, tender, painful or irritating.

What is a papular lesion?

Is pruritus life threatening?

In some cases, pruritus may be a symptom of a serious or life-threatening condition known as anaphylaxis (life-threatening allergic reaction) that should be immediately evaluated in an emergency setting.

Is there a blood disease that causes itching?

What blood disease causes itchy skin?

As well as leukaemia, two other blood cancers are distinctly notorious for causing itchy skin: lymphoma and polycythaemia vera (PV). Generally speaking, itching in lymphoma is caused by a specific type called Hodgkin’s lymphoma (HL), with 1 in 3 HL patients experiencing it as a symptom before their diagnosis.

Can a blood disorder cause itchy skin?

Warning sign of a disease inside your body. Long-standing itch can be a sign of several diseases, including: Blood disease.

What is pruritic papular eruption of HIV?

What is pruritic papular eruption of HIV? Pruritic papular eruption of HIV (Human Immunodeficiency Virus) is the most common rash associated with HIV infection, and is often the presenting sign in an otherwise asymptomatic HIV-positive person. Who gets pruritic papular eruption of HIV?

What is papular urticaria?

Papular urticaria is an allergic reaction to insect bites or stings. The condition causes itchy red bumps on the skin. Some bumps can become fluid-filled blisters, called vesicles or bullae, depending on size. Papular urticaria is more common in children between the ages of 2 and 10. It can affect adults and children at any age, however.

Which histologic findings are characteristic of papular urticaria (papular rash)?

Papular urticaria is usually a clinical diagnosis. A biopsy may support the diagnosis, as insect bites have a characteristic microscopic appearance. The histopathology of papular urticaria includes mild dermal oedema, extravasation of erythrocytes, interstitial eosinophils, and exocytosis of lymphocytes.

How long do papular urticaria spots last?

The spots remain for days to weeks and can leave postinflammatory pigmentation or hypopigmented scars, especially if they have been scratched deeply. What are the complications of papular urticaria?

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