What drugs interact with Reclast?
Medications that may interact with Reclast include aminoglycoside antibiotics, such as amikacin, gentamicin, kanamycin, neomycin, streptomycin, and tobramycin. Combining Reclast and these antibiotics puts you at an increased risk for low levels of calcium in the blood, as well as severe kidney problems.
Is zoledronic acid a chemo drug?
Zoledronic acid (Zometa) is not cancer chemotherapy, and it will not slow or stop the spread of cancer. However, it can be used to treat bone disease in patients who have cancer. Zoledronic acid is in a class of medications called bisphosphonates.
Does zoledronic acid make you tired?
Vomiting. Constipation. Flu-like symptoms; mild fever sometimes accompanied by malaise, chills, fatigue and flushing. Usually occurs with first treatment with zoledronic acid only.
What is the most common side effect of zoledronic acid?
Fever is the most common adverse effect associated with zoledronic acid infusion. Flu-like syndromes including fever, chills, bone pain, and/or arthralgias and myalgias have also occasionally been reported. These symptoms generally did not require treatment and resolved within 24 to 48 hours.
Can you drink alcohol after zoledronic acid?
The drinking of alcohol (in small amounts) does not appear to affect the safety or usefulness of zoledronic acid. pregnancy. It is best to use birth control while being treated with zoledronic acid. Tell your doctor right away if you or your partner becomes pregnant.
How long does zoledronic acid stay in your system?
The excretion of zoledronic acid by the kidney does not depend on the dose or the infusion time (Chen et al 2002). The drug can be detected in urine in trace amounts up to 28 days after the infusion, although adequate amounts are present in urine only in the first 24 hours (Chen et al 2002).
Can you drive after zoledronic acid infusion?
Ask your doctor for advice before taking any medicine while you are pregnant or breast- feeding. There have been very rare cases of drowsiness and sleepiness with the use of Zoledronic Acid. You should therefore be careful when driving, using machinery or performing other tasks that need full attention.
Does zoledronic acid weaken the immune system?
In addition to its effects on bone cells, ZOL has profound effects on the immune system, including a plethora of immune cell subsets expressing the mevalonate pathway enzymes, leading to a general increase in anti-tumour immunity [65].
How long does zoledronic acid infusion stay in the body?
Zoledronic acid medication is a long-acting drug. As such, it stays in your body longer than 12 months (probably more than 24 months). Therefore, delaying your treatment for a number of months will not put you at a higher risk of sustaining fragility fracture nor cause significant decline in your bone mineral density.
Can you drink alcohol with zoledronic acid?
How will I feel after zoledronic acid infusion?
The majority of the side effects, such as fever and chills, pain in the muscles or joints, and headache, occur within the first three days following the dose of Zoledronic acid 5 mg. The symptoms are usually mild to moderate and go away within three days.
What does zoledronic acid do to your teeth?
A Link between Poor Dental Health and Risk of Osteonecrosis of the Jaw. Zoledronic acid and similar drugs, known as bisphosphonates, interfere with the breakdown of bone tissue that results when cancer cells grow in the bone.
Can I drive home after zoledronic acid infusion?
Ask your doctor, pharmacist or nurse for advice before taking this medicine. If you feel dizzy while taking Zoledronic acid 5 mg, do not drive or use machines until you feel better.