What are the side effects of strontium citrate?
Strontium ranelate might cause side effects such as stomach pain, diarrhea, and headache in some people. This form of strontium is not available in the U.S. Taking very high doses of strontium by mouth is POSSIBLY UNSAFE. High doses of strontium might damage the bones.
Why was strontium bone Maker discontinued?
On October 1, 2014 the European Medicines Agency’s Pharmacovigilance Risk Assessment Committee (PRAC) recommended that strontium ranelate (Protelos/Osseor, Servier) no longer be used to treat osteoporosis because of data demonstrating serious negative side effects.
When is the best time to take strontium citrate?
Strontium comes in 2 gram sachets. The dose is one sachet every day. It should be taken on an empty stomach at least two hours after eating. The best time to take it is at night before going to bed.
What is the difference between strontium ranelate and strontium citrate?
Commonly available Sr formulations include Strontium Ranelate (SrR), which is approved for the treatment of OP in postmenopausal women in Europe, and Strontium Citrate (SrC), which is available Over The Counter (OTC) in US. Sr occurs naturally as mineral deposits of strontium sulfate and strontium carbonate.
Is strontium citrate safe to take for osteoporosis?
It is FDA-approved for the prevention and treatment of osteoporosis in postmenopausal women and to reduce risk of invasive breast cancer in postmenopausal women at high risk or with osteoporosis.
Does strontium make bones stronger?
Dangerous at High Doses However, years of strontium ranelate prescriptions as the European drug Protelos have not helped as hoped. Strontium ranelate was considered safe and shown to reduce fracture risk before going to market, but its bone-building effects were less beneficial than expected.
Can strontium cause kidney stones?
In addition, the kidneys process strontium similarly to calcium. The amount of strontium and apatite in kidney stones is correlated.
Can strontium cause heart problems?
Calcium, magnesium and strontium have all been implicated in both musculoskeletal and cardiovascular health and disease.
What foods contain strontium citrate?
In your diet, you get it mainly from seafood, but you can also get small amounts of it in whole milk, wheat bran, meat, poultry, and root vegetables.
Does strontium cause kidney stones?
X-ray fluorescence analysis clearly shows that strontium co-localizes with calcium in calcium based stone formation. In addition, the kidneys process strontium similarly to calcium. The amount of strontium and apatite in kidney stones is correlated.
Where is strontium in food?
Strontium is found in relatively high concentrations in spices, whole grains, leafy green vegetables such as spinach and kale, seafood, root vegetables like carrots and parsnips, and legumes like beans, lentils and peas.
How do you take strontium ranelate?
Strontium ranelate aims to overcome the problems associated with strontium. Patients take 2 g of granules in water. As the slow absorption is reduced by food, the dose should be taken at bedtime at least two hours after eating. Binding in the gut can reduce the absorption of some antibiotics.
Can calcium and strontium be taken together?
Do not take products containing calcium within two hours before or after taking your strontium. Your healthcare professionals may already be aware of this interaction and may be monitoring you for it.
Which foods are high in strontium?
The bran of grains, the peel of root vegetables, spinach, lettuce, carrots, peas, and beans all contain relatively high levels.
- Brazil nuts are also a hearty source of natural strontium.
- Dairy products like milk and cheese are a good source of natural strontium too.
When should strontium ranelate be taken?
Strontium ranelate should be taken at bed time, at least two hours after eating, so it can be absorbed properly. Wait at least two hours before having any food, although you can have water if you wish.
Where can I get strontium?
Strontium is a mineral found in seawater and soil. In your diet, you get it mainly from seafood, but you can also get small amounts of it in whole milk, wheat bran, meat, poultry, and root vegetables. Strontium is similar to calcium.
Do nuts contain strontium?
The bran of grains, the peel of root vegetables, spinach, lettuce, carrots, peas, and beans all contain relatively high levels. Brazil nuts are also a hearty source of natural strontium.
Why is strontium ranelate not approved by the FDA?
The European Pharmacovigilance Risk Assessment Committee (PRAC) recommended restriction in the use of strontium ranelate, based on a routine benefit-risk assessment of the medicine, which included data showing a possible increased risk of heart problems, including heart attacks.
Is strontium ranelate effective?
Strontium ranelate slows down the cells that break down bone, and may also increase the activity of the bone building cells. Although it works in a different way from other osteoporosis medications, strontium ranelate doesn’t appear to be any more effective in reducing your risk of broken bones.
What food is high in strontium?
What drugs are used to treat osteoporosis?
Drugs such as denosumab, teriparatide and abaloparatide can be used by anyone with osteoporosis, but are more likely to be recommended for people with unique circumstances, including severe osteoporosis with very low bone density, multiple fractures, steroid use and young age. These drugs,…
What is osteoporosis and how is it treated?
About Osteoporosis: Osteoporosis is the thinning of bone tissue and loss of bone density over time. The following list of medications are in some way related to, or used in the treatment of this condition.
Are there any side effects to hormone therapy for osteoporosis?
Hormones, such as estrogen, can play a role in osteoporosis prevention and treatment. However, there has been some concern about potential side effects tied to the use of hormone therapy. Current recommendations say to use the lowest dose of hormones for the shortest period of time.
What is Estrace used for?
Estradiol ( Estrace, Vivelle-Dot, Climara) is a moderately priced drug used to treat hot flashes and osteoporosis. It is also used to treat women with low estrogen levels or those who have had their ovaries removed. This drug is more popular than comparable drugs.