What is the function of trabecular meshwork?

The trabecular meshwork, located within the iridocorneal angle, is the main pathway for drainage of aqueous humor (AH) out of the eye, and its dysfunction is responsible for the IOP elevation.

Where is the trabecular meshwork located?

The trabecular meshwork is the spongy tissue located near the cornea through which aqueous humor flows out of the eye.

What causes blockage of trabecular meshwork?

Pigment dispersion, where tiny fragments or granules from the iris (the colored part of the eye) can circulate in the aqueous humor (the fluid within the front portion of the eye) and block the trabecular meshwork, the tiny drain for the eye’s aqueous humor.

What is another name for trabecular meshwork?

cribriform meshwork
Juxtacanalicular tissue (also known as the cribriform meshwork) – Lies immediately adjacent to Schlemm’s canal, composed of connective tissue ground substance full of glycoaminoglycans and glycoproteins. This thin strip of tissue is covered by a monolayer of endothelial cells.

Is Schwalbe’s line pigmented?

When pigment is found anterior to or along Schwalbe’s line, it is called a Sampaolesi’s line. Although this can be idiopathic, the presence of a Sampaolesi’s line can be associated with both pigmentary syndrome and glaucoma and pseudoexfoliation syndrome and glaucoma.

What happens when trabecular meshwork is blocked?

Malfunction in the trabecular meshwork (TM), leading to blockage of Schlemm’s canal (SC), often leads to a dangerously increased IOP in primary open angle glaucoma (POAG) – and yet we don’t even know why this problem occurs.

What chamber is canal of Schlemm?

anterior chamber
eye anatomy and function trabecular meshwork and flows into Schlemm’s canal, a ringlike passageway around the outer angle of the anterior chamber in front of the iris. From the canal the liquid enters the veins.

What causes blockage in trabecular meshwork?

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