What does RPR titer of 1/4 mean?
The RPR antibody (a non-treponemal or reaginic antibody) titer of 1:4 may be associated with: 1) reinfection syphilis (immunity brought about by previous syphilis infection is incomplete)
What does an RPR titer of 1 1 mean?
A confirmed case of syphilis was defined as an RPR titer ≥1:1 with a positive TPHA result. All positive results, including syphilis diagnoses, were communicated with patients and attending clinicians in order to provide appropriate therapy.
What is RPR titre?
A rapid plasma reagin (RPR) test is a blood test used to screen you for syphilis. It works by detecting the nonspecific antibodies that your body produces while fighting the infection. Syphilis is a sexually transmitted infection (STI) caused by the spirochete bacterium Treponema pallidum.
What does positive RPR mean?
A positive test result may mean that you have syphilis. If the screening test is positive, the next step is to confirm the diagnosis with a more specific test for syphilis, such as FTA-ABS. The FTA-ABS test will help distinguish between syphilis and other infections or conditions.
How do you interpret RPR results?
Reactive RPR results should always be considered as true positives among people at risk and an increase in RPR of two titres from the previous RPR considered a likely new infection. False negative test results can occur among people who have: Very early syphilis and are tested before the test is measurable in the blood.
What does RPR Positive mean?
A positive test result may mean that you have syphilis. If the screening test is positive, the next step is to confirm the diagnosis with a more specific test for syphilis, such as FTA-ABS . The FTA-ABS test will help distinguish between syphilis and other infections or conditions.
How do you treat positive RPR?
Penicillin G, administered parenterally, is the preferred drug for treating patients in all stages of syphilis. The preparation used (i.e., benzathine, aqueous procaine, or aqueous crystalline), dosage, and length of treatment depend on the stage and clinical manifestations of the disease.
What does RPR titer of 1/32 mean?
This means that the RPR pr VDRL test remains reactive. The only way to know if it is an infection that needs treatment is to compare titers. If the titer is four fold lower than pervious (i.e. 1:128 down to 1:32), this means that the person has been appropriately treated and no further therapy is needed (CDC, 2010).
What does it mean if a titer is negative?
That means that you have adequate immunity to a particular infectious disease. If titer results are negative, this means there is no immunity to a specific disease. Your school or work may require you to get a vaccination.
What can cause a positive RPR?
Historically, false-reactive RPR test results have been observed in people with systemic infections unrelated to syphilis, such as tuberculosis, rickettsial diseases, and endocarditis. False-reactive RPR testing also has been previously observed following immunization (specifically following smallpox vaccine).
What does a titer of 1 320 mean?
ANA results are reported using a titer, such as 1:320. Generally, the higher the titer, the more likely the patient is to have a connective tissue disorder. The titer shows how many times the patient’s serum was diluted before the antibodies could no longer be detected.
What does a RPR titer of 1 128 mean?
Both the RPR and VDRL are quantitative results (CDC, 2013). High titers such as 1:128 mean that there is more antibody present than low titers such as 1:2. The titer is used to determine whether or not an individual has been effectively treated.
Does RPR always remain positive?
This is known as a false negative. False negatives tend to be more common in the initial and end stages of infection. Among people who are in the secondary (middle) stage of infection, the RPR test result is nearly always positive. The RPR test also can produce false-positive results, suggesting you have syphilis when you actually don’t.
Does RPR stay positive?
It doesn’t mean anything; these tests remain positive despite cure. If there is real suspicion of syphilis, an RPR (or VDRL, equivalent to RPR) will then be done. As long as the RPR/VDRL remains negative or very weakly positive, it will indicate you were cured and not reinfected.
What does a positive RPR blood test mean?
Small,painless sores (chancres) at the place where syphilis invaded your body
What causes a false positive RPR?
A healthcare provider will ask you to sit in a comfortable chair or lie down on a cot or a gurney.